Patent · US Active

System for controlled release of an active principle and method for preparation

US8709481B2 · kind B2 · utility

0Cited by

5References

15Claims

0Family size

Assignees

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
Universite De Montpellier · FR

Inventors

Michel Vert · Castelnau-le-Lez, FR
Laurent Christian L. Leclercq · Montpellier, FR
Mahfoud Boustta · Rouen, FR

Key dates

Filing date	Jul 18, 2008
Grant date	Apr 29, 2014
Priority date	—
Expiry date	Aug 1, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A system for controlled release of an active principle, includes at least (a) a degradable polymer matrix which produces acid compounds and (b) at least one acid-sensitive complex of an active principle having at least one electrostatic charge and a complexing polyelectrolyte partner of opposite charge which complexes with the active principle. A method for preparation of such a system is described. The release of the active principle (7P) is prolonged over 18 days (ternary system PMLA/7P/PLAGA) in comparison to binary systems (7P/PLAGA) and (PMLA/7P).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.