Method for identifying modulators of GPCR GPR1 function
US8709734B2 · kind B2 · utility
1Cited by
1References
32Claims
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Assignee
Inventor
Key dates
| Filing date | Oct 1, 2010 |
| Grant date | Apr 29, 2014 |
| Priority date | — |
| Expiry date | Oct 1, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to the identification of Humanin and derivatives thereof as ligands of the GPR1 GPCR (G-protein coupled receptor). The invention encompasses the use of the interaction of GPR1 polypeptides and Humanin polypeptides as the basis of screening assays for agents that modulate the activity of the GPR1 receptor. The invention also encompasses diagnostic assays based upon the GPR1/Humanin polypeptide interaction, as well as kits for performing diagnostic and screening assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.