Patent · US Active

Crystalline form of zofenopril calcium

US8710241B2 · kind B2 · utility

0Cited by
3References
16Claims
0Family size

Assignee

Inventor

Key dates

Filing dateAug 8, 2008
Grant dateApr 29, 2014
Priority date
Expiry dateMay 14, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D207/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a novel anhydrous crystalline form of zofenopril calcium of formula (I), chemically known as (4S)-1-[(2S)-3-(benzoylthio)-2-methylpropionyl]-4-(phenylthio)-L-proline calcium salt or hemi-calcium salt. The present invention further relates to a process for the preparation of the new crystalline form of zofenopril calcium, its use in pharmaceutical compositions and the use of the new crystalline form and compositions in the treatment of hypertension and various other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.