Packaging cells for producing retrovirus pseudotyped with an E2 alphavirus glycoprotein
US8715640B2 · kind B2 · utility
5Cited by
28References
8Claims
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Key dates
| Filing date | Jan 15, 2010 |
| Grant date | May 6, 2014 |
| Priority date | — |
| Expiry date | Jan 15, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.