Patent · US Active

Manipulation of cells on a droplet actuator

US8716015B2 · kind B2 · utility

25Cited by
86References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 15, 2008
Grant dateMay 6, 2014
Priority date
Expiry dateNov 19, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/2575
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of inoculating a culture medium including providing a droplet including a single cell type on a droplet actuator and inoculating a culture medium with the droplet. A method of providing a metabolically useful substance to a cell culture, including providing a droplet actuator including a cell culture droplet loaded thereon, the sample droplet including cells and a cell culture medium, and a second droplet comprising a metabolically useful substance. The method also includes conducting one or more droplet operations to combine the cell culture droplet with the second droplet on the droplet actuator. Related methods, droplet actuators, and systems are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.