Patent · US Active

Reprogrammation of eukaryotic cells with engineered microvesicles

US8716020B2 · kind B2 · utility

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7Claims

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Assignee

INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) · FR

Inventors

Philippe Mangeot · Lyon, FR
Vincent Lotteau · Val-de-Reuil, FR
Marc Peschanski · Créteil, FR
Mathilde Girard · Dole, FR

Key dates

Filing date	Nov 10, 2010
Grant date	May 6, 2014
Priority date	—
Expiry date	Nov 10, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/608
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a non-genetic, detergent-free, bacteria-free method for reprogramming a eukaryotic cell, in particular for obtaining induced pluripotent stem cells (iPS), by using engineered microvesicles carrying at least one reprogramming transcription factor, wherein said engineered microvesicles are virus-free.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.