Patent · US Active

Identification of antigen or ligand-specific binding proteins

US8716194B2 · kind B2 · utility

1Cited by

21References

14Claims

0Family size

Assignee

4-Antibody AG · CH

Inventors

Ulf Grawunder · Basel, CH
Jörn Stitz · Basel, CH

Key dates

Filing date	Sep 29, 2011
Grant date	May 6, 2014
Priority date	—
Expiry date	Sep 29, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC40B30/04
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins. The methods disclosed herein allow the expression of diverse collections of binding proteins from at least one vector construct, which optionally can give rise to collections of diverse binding proteins upon transfer and expression into vertebrate host cells in situ.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.