Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases
US8716288B2 · kind B2 · utility
2Cited by
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16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 10, 2013 |
| Grant date | May 6, 2014 |
| Priority date | — |
| Expiry date | May 10, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel pharmaceutical composition of benproperine derivatives for preventing and treating angiogenesis-related diseases. The benproperine derivatives and pharmaceutically acceptable salts thereof according to the present invention inhibit cancer cell migration and the angiogenesis of vascular endothelial cells, and therefore can be effectively used not only as an anticancer agent, but also as an agent for preventing and treating diseases caused by abnormal angiogenesis, such as diabetic retinopathy and corneal transplant rejection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.