Solid compositions

US8716454B2 · kind B2 · utility

Assignee

• Abb Vie Inc. · US

Inventors

• Simon Kullmann · Neustadt an der Weinstraße, DE
• Ulrich Westedt · Schriesheim, DE
• Mirko Pauli · Ludwigshafen, DE
• Rudolf Schroeder · Monsheim, DE
• Gerd Woehrle · Eppelheim, DE
• Tanja Heitermann · Wiesloch, DE
• Renato Koenig · Haßloch, DE
• Madlen Thiel · Schifferstadt, DE
• Yi Gao · Vernon Hills, US
• Jianwei Wu · Potomac, US
• Bryan K. Erickson · Pleasant Prairie, US

Key dates

• Filing date: Jun 9, 2011
• Grant date: May 6, 2014
• Expiry date: Feb 18, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention features solid compositions comprising Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, in an amorphous form. In one embodiment, Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, is formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.