Induction of p53 expression by neutralization of neuropilin-2 for the treatment of cancers
US8722043B2 · kind B2 · utility
7Cited by
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9Claims
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Key dates
| Filing date | Aug 26, 2009 |
| Grant date | May 13, 2014 |
| Priority date | — |
| Expiry date | Jun 21, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of anti-human neuropilin-2 antibodies, or of ligands of human neuropilin-2 derived from these antibodies, for obtaining a medicament intended to increase p53 expression and to induce tumor cell apoptosis in the context of an anticancer treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.