Synthetic glucopyranosyl lipid adjuvants
US8722064B2 · kind B2 · utility
21Cited by
164References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 4, 2010 |
| Grant date | May 13, 2014 |
| Priority date | — |
| Expiry date | Nov 14, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/575
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, particularly, glucopyranosyl lipid adjuvant (GLA) compounds, having the following structure (I) are provided:or a pharmaceutically acceptable salt thereof, wherein L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, Y1, Y2, Y3, Y4, R1, R2, R3, R4, R5, R6, are as defined herein. Pharmaceutical compositions, vaccine compositions, and related methods for inducing or enhancing immune responses, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.