Preparation of submicron sized nanoparticles via dispersion lyophilization
US8722091B2 · kind B2 · utility
2Cited by
177References
47Claims
0Family size
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Key dates
| Filing date | Aug 17, 2004 |
| Grant date | May 13, 2014 |
| Priority date | — |
| Expiry date | Jul 2, 2026 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J13/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase having the poorly water soluble organic compound therein. The method is preferably used to prepare nanoparticles of a poorly water soluble, pharmaceutically active compound suitable for in vivo delivery, particularly by parenteral routes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.