Patent · US Active

Auristatin derivatives and use thereof

US8722629B2 · kind B2 · utility

1Cited by

2References

21Claims

0Family size

Assignee

SEATTLE GENETICS, INC. · US

Inventors

Hans-Georg Lerchen · Leverkusen, DE
Beatrix Stelte-Ludwig · Wülfrath, DE
Sven Golfier · Berlin, DE
Joachim Schuhmacher · Wuppertal, DE
Ursula Krenz · Leichlingen, DE

Key dates

Filing date	Jun 6, 2011
Grant date	May 13, 2014
Priority date	—
Expiry date	Jun 6, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application relates to novel derivatives of monomethylauristatin F, to processes for preparing these derivatives, to the use of these derivatives for treating and/or preventing diseases, and also to the use of these derivatives for preparing medicaments for treating and/or preventing diseases, more particularly hyperproliferative and/or angiogenic disorders such as, for example, cancerous disorders. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.