Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile
US8722890B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 14, 2012 |
| Grant date | May 13, 2014 |
| Priority date | — |
| Expiry date | Aug 14, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that inhibit protein kinases such as Aurora-kinases and the VEGFR and PDGFR families of kinases, with an improved safety profile due to low CYP3A4 inhibition, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.