B1-robust and T1-robust species suppression in MRI
US8723516B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 26, 2010 |
| Grant date | May 13, 2014 |
| Priority date | — |
| Expiry date | Jan 26, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/5659
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An MRI multi-echo data acquisition sequence (REFUSAL=REFocusing Used to Selectively Attenuate Lipids) includes a spectrally-selective re-focusing RF pulse. The REFUSAL pulse can be non-spatially selective or spatially-selective. The REFUSAL pulse selectively refocuses water spins and avoids refocusing lipid spins. The REFUSAL pulse ideally maximizes refocusing for water and minimizes any lipid refocusing, with built-in robustness to B0-inhomogeneity and B1-inhomogeneity. Following the REFUSAL pulse, the remainder of the echo train continues in a conventional fashion. Only those spins that were refocused with the spectrally selective REFUSAL pulse continue to evolve coherently and generate a train of echoes. Those spins that were minimally refocused are spoiled and thus do not contribute signal to the final image. To incorporate a longer duration REFUSAL pulse, the echo spacing can be made non-uniform such that the first echo spacing is longer than the remainder of the echo spacings in the echo train.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.