Multivalent fibronectin based scaffold domain proteins
US8728483B2 · kind B2 · utility
36Cited by
51References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 26, 2012 |
| Grant date | May 20, 2014 |
| Priority date | — |
| Expiry date | Jun 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.