Compositions and methods for making and using laminin nanofibers
US8728817B2 · kind B2 · utility
15Cited by
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25Claims
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Key dates
| Filing date | Mar 10, 2011 |
| Grant date | May 20, 2014 |
| Priority date | — |
| Expiry date | Dec 5, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methodologies and parameters for fabrication of the hybrid biomaterial by blending pure laminin or complex extracts of tissues containing laminin with biopolymers such as polycaprolactone (PCL), polylactic/polyglycolic acid copolymer (PLGA) or Polydioxanone (PDO) in fluoroalcohols (HFP, TFA), fabrication of substrates and scaffolds and devices from the hybrid biomaterial in forms such as films, nanofibers by electrospinning or microspheres, and the biological or biomedical use of the material or devices derived from it.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.