Purification of immunoglobulins
US8728828B2 · kind B2 · utility
13Cited by
9References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2005 |
| Grant date | May 20, 2014 |
| Priority date | — |
| Expiry date | Nov 10, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/824
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilized, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is above 0.65 and the median particle diameter is between 65-84 μm. The carbohydrate material is preferably highly cross-linked agarose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.