Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
US8729029B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 20, 2009 |
| Grant date | May 20, 2014 |
| Priority date | — |
| Expiry date | Dec 13, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.