Patent · US Active

Peptide derivatives and use thereof as carriers for molecules in the form of conjugates

US8729029B2 · kind B2 · utility

4Cited by
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21Claims
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Key dates

Filing dateOct 20, 2009
Grant dateMay 20, 2014
Priority date
Expiry dateDec 13, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.