Fluid path system for dissolution and transport of a hyperpolarized material

US8731640B2 · kind B2 · utility

Assignee

• General Electric Company · US

Inventors

• John Arthur Urbahn · Saratoga Springs, US
• Jan Henrik Ardenkjaer-Larsen · Malmö, SE
• Andrew Michael Leach · Clifton Park, US
• Eric John Telfeyan · Guilderland, US
• David Key Dietrich · Schenectady, US
• David Brandon Whitt · Albany, US
• Peter Miller · New London, US
• Ernst Wolfgang Stautner · Niskayuna, US

Key dates

• Filing date: Jan 13, 2012
• Grant date: May 20, 2014
• Expiry date: Jan 13, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/25
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A fluid path system includes a vial containing a pharmaceutical product therein. A dissolution fluid path is also included in the fluid path system, the dissolution fluid path having an output end in fluid communication with the vial and an input end attached to a pressure vessel containing a dissolution medium. A delivery fluid path is also included in the system having a first end hermetically attached to the vial to transport therefrom a mixture of dissolved pharmaceutical product and dissolution medium and a second end connected to a receiving vessel to receive the mixture. A dissolution fluid path valve is positioned between the pressure vessel and the dissolution fluid path to control flow of the dissolution medium, and a delivery fluid path valve is also included in the fluid path system to control flow of the mixture from the delivery fluid path to the receiving vessel.