Protease activated cytokines

US8734774B2 · kind B2 · utility

Assignee

• University of Rochester · US

Inventors

• John G. Frelinger · Pittsford, US
• John Puskas · Rochester, US
• Baek Kim · Rochester, US
• Mark A. Sullivan · Fairport, US

Key dates

• Filing date: Mar 31, 2011
• Grant date: May 27, 2014
• Expiry date: Mar 31, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are chimeric nucleic acid sequences encoding chimeric polypeptides. Also provided herein are chimeric polypeptides. Further provided herein are methods of treating a subject with or at risk of developing a cancer. The methods comprise selecting a subject with or at risk of developing a cancer, and administering to the subject an effective amount of the chimeric polypeptides provided herein.