Light targeting molecules and uses thereof

US8734795B2 · kind B2 · utility

Assignee

• BIOGEN IDEC MA INC. · US

Inventors

• Xinzhong Wang · Wayland, US
• Veronique Bailly · Boxborough, US
• Alexey A. Lugovskoy · Woburn, US
• Graham K. Farrington · Acton, US
• Christilyn Graff · Cambridge, US
• Scott Glaser · San Diego, US

Key dates

• Filing date: Oct 30, 2009
• Grant date: May 27, 2014
• Expiry date: Nov 23, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

LIGHT-targeting molecules (e.g., LIGHT fusion molecules), anti-HER2 antibody molecules, compositions, e.g., pharmaceutical compositions thereof, are disclosed. Methods of using these molecules to treat, prevent and/or diagnose hyperproliferative, e.g., neoplastic, diseases or conditions, including, but not limited to, cancer and metastasis are also provided.