Carrier immunoglobulins

US8734796B2 · kind B2 · utility

Assignee

• AMGEN INC. · US

Inventors

• Kenneth W. Walker · Newbury Park, US
• Yue-Sheng Li · Cambridge, US
• Thomas C. Boone · Newbury Park, US
• Frederick W. Jacobsen · Newbury Park, US
• Hosung Min · Westlake Village, US
• Jane Talvenheimo · Seattle, US
• Taruna Arora · Palo Alto, US
• George Doellgast · Winston-Salem, US

Key dates

• Filing date: Mar 19, 2010
• Grant date: May 27, 2014
• Expiry date: Dec 29, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed is an isolated antigen binding protein, such as but not limited to, an antibody or antibody fragment. Also disclosed are pharmaceutical compositions and medicaments comprising the antigen binding protein, isolated nucleic acid encoding it, vectors, host cells, and hybridomas useful in methods of making it. In some embodiments the antigen binding protein comprises one to twenty-four pharmacologically active chemical moieties conjugated thereto, such as a pharmacologically active polypeptide.