Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
US8735124B2 · kind B2 · utility
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Key dates
| Filing date | Mar 15, 2012 |
| Grant date | May 27, 2014 |
| Priority date | — |
| Expiry date | Apr 27, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/08001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An isolated polypeptide comprising the amino acid sequence of serum paraoxonase (PON1) having catalytic efficiency of kcat/KM≈106-5·107 M−1min−1 for a G-type organophosphate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.