Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions

US8735426B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Robert Frank · Aachen, DE
• Gregor Bahrenberg · Monschau, DE
• Thomas Christoph · Aachen, DE
• Klaus Schiene · Goldkronach, DE
• Jean De Vry · Stolberg, DE
• Derek Saunders · Aachen, DE
• Bernd Sundermann · Aachen, DE
• Jeewoo Lee · Ansan-si, KR

Key dates

• Filing date: Apr 11, 2008
• Grant date: May 27, 2014
• Expiry date: Jan 8, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds corresponding to formula I:which act as vanilloid receptor ligands, pharmaceutical compositions containing such compounds, a process for the producing such compounds, and the use thereof to treat or inhibit pain and/or various other disorders or conditions.