Patent · US Active

Histone demethylase inhibitors and methods for using the same

US8735622B2 · kind B2 · utility

1Cited by

0References

16Claims

0Family size

Assignee

The Regents of the University of Colorado, a Body Corporate · US

Inventors

Xiang Wang · Foster City, US
Wenqing Xu · Beijing, CN

Key dates

Filing date	Nov 30, 2012
Grant date	May 27, 2014
Priority date	—
Expiry date	Nov 30, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/86
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention provides compounds, or derivatives or prodrugs thereof, that comprise a methyllysine mimic, and an α-ketoglutarate mimic that are attached through a linker and methods for using and producing the same. In some embodiments, compounds of the invention are of the formula: M-L-K, or a derivative or a prodrug thereof, wherein M is a methyllysine mimic, L is a linker, and K is an α-ketoglutarate mimic.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.