Heteroclitic analogs and related methods
US8741576B2 · kind B2 · utility
17Cited by
14References
12Claims
0Family size
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Key dates
| Filing date | Apr 5, 2002 |
| Grant date | Jun 3, 2014 |
| Priority date | — |
| Expiry date | Nov 5, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Heteroclitic analogs of Class I epitopes are prepared by providing conservative or semi-conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding wildtype epitopes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.