Crystal structure of isoglutaminyl cyclase

US8741614B2 · kind B2 · utility

Assignee

• PROBIODRUG AG · DE

Inventors

• Anett Stephan · Halle (Saale), DE
• Stephan Schilling · Halle (Saale), DE
• Jens-Ulrich Rahfeld · Lieskau, DE
• Michael Wermann · Halle (Saale), DE
• Christoph Parthier · Halle (Saale), DE
• Hans-Ulrich Demuth · Halle (Saale), DE
• David Ruiz-Carillo · Singapore, SG
• Milton T. Stubbs · Halle (Saale), DE

Key dates

• Filing date: Oct 28, 2011
• Grant date: Jun 3, 2014
• Expiry date: Oct 28, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G16C20/50
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A crystal comprising human isoglutaminyl cyclase having a characterized space group of P1211 and unit cell dimensions of +/−5% of a=126.51 Å, b=109.68 Å, c=159.53 Å, α=90.0°, β=104.9° and γ=90.0°.