Differentiation of pluripotent stem cells to definitive endoderm lineage
US8741643B2 · kind B2 · utility
6Cited by
74References
1Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 18, 2007 |
| Grant date | Jun 3, 2014 |
| Priority date | — |
| Expiry date | Jun 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.