Reprogramming T cells and hematopoietic cells
US8741648B2 · kind B2 · utility
15Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 4, 2010 |
| Grant date | Jun 3, 2014 |
| Priority date | — |
| Expiry date | Jun 16, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E60/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.