Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methyl-benzoate hydrochloride, methods for preparing the same and use of the same

US8741952B2 · kind B2 · utility

Assignees

• SHANDONG LUYE PHARMACEUTICAL CO., LTD. · CN
• Youxin Li

Inventors

• Youxin Li · Langenfeld, DE
• Wanhui Liu · Yantai, CN
• Yang Lv · Suzhou, CN
• Guanhua Du · Beijing, CN
• Qingguo Meng · Shandong, CN
• Mina Yang · Shandong, CN
• Fengmei Zhou · Yantai, CN
• Ju Li · Taipei, TW
• Xuemei Zhang · Foshan, CN

Key dates

• Filing date: Mar 18, 2013
• Grant date: Jun 3, 2014
• Expiry date: Mar 18, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C215/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.