Patent · US Active

Optimized FC variants

US8742074B2 · kind B2 · utility

12Cited by

0References

9Claims

0Family size

Assignee

Laboratoire Francais du Fractionnement et des Biotechnologies · FR

Inventors

Christian Behrens · Palaiseau, FR
Sylvie Jorieux · Lomme, FR
Abdelhakim Kharrat · Ramonville-Saint-Agne, FR
Khalil Bouayadi · Toulouse, FR
Philippe Mondon · Donneville, FR
Celine Monnet-Mars · Lambersart, FR

Key dates

Filing date	Mar 19, 2010
Grant date	Jun 3, 2014
Priority date	—
Expiry date	Mar 19, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A variant of a parent polypeptide including an Fc region, which variant exhibits increased binding to FcRn as compared to the parent polypeptide and includes at least one amino acid modification in the Fc region.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.