Panel of micrornas that silence the MCL-1 gene and sensitize cancer cells to ABT-263
US8742083B1 · kind B1 · utility
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Key dates
| Filing date | Dec 23, 2010 |
| Grant date | Jun 3, 2014 |
| Priority date | — |
| Expiry date | Mar 18, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/178
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
MicroRNAs (miRNAs) that sensitize cancer cells to Bcl-2 family protein inhibitors are identified and described. Oligonucleotide panels, arrays and methods using the sensitizing miRNAs are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.