Patent · US Active

Purine nucleoside analogues for treating flaviviridae including hepatitis C

US8742101B2 · kind B2 · utility

23Cited by
47References
38Claims
0Family size

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Inventors

Key dates

Filing dateNov 13, 2008
Grant dateJun 3, 2014
Priority date
Expiry dateApr 10, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/23
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention is directed to a method for treating a host, especially a human, infected with hepatitis C, flavivirus and/or pestivirus, comprising administering to that host an effective amount of an anti-HCV biologically active pentofuranonucleoside where the pentofuranonucleoside base is an optionally substituted 2-azapurine. The optionally substituted pentofuranonucleoside, or a salt or prodrug thereof, may be administered alone or in combination with one or more optionally substituted pentofuranonucleosides or other anti-viral agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.