Nasolacrimal drainage system implants for drug therapy

US8747884B2 · kind B2 · utility

Assignee

• Mati Therapeutics, Inc. · US

Inventors

• Eugene de Juan, Jr. · San Francisco, US
• Stephen Boyd · Murrieta, US
• Cary J. Reich · Los Gatos, US
• Alan R. Rapacki · Redwood City, US
• Hanson S. Gifford, III · Woodside, US
• Mark Deem · Mountain View, US

Key dates

• Filing date: Jul 18, 2011
• Grant date: Jun 10, 2014
• Expiry date: Jul 31, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2250/0087
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.