Hepatitis B virus compositions and methods of use
US8748373B2 · kind B2 · utility
12Cited by
0References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2008 |
| Grant date | Jun 10, 2014 |
| Priority date | — |
| Expiry date | Apr 23, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/6036
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polypeptide comprising a preS1 region of hepatitis B virus (HBV), or a fragment thereof, and/or the preS2 region of HBV or a fragment thereof, and methods of use to inhibit virus infection are disclosed. A lentivirus comprising hepatitis B virus (HBV) envelope proteins, or a fragment thereof, and/or the L envelope protein of HBV and/or the M envelope protein of HBV or a fragment thereof, and/or the S envelope protein of HBV or a fragment thereof, and methods of use of this lentivirus HBV pseudovirus as a gene therapy to target hepatocytes for the administration of therapeutic agents are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.