Antineoplastic compounds and pharmaceutical compositions thereof
US8748411B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 5, 2006 |
| Grant date | Jun 10, 2014 |
| Priority date | — |
| Expiry date | Jun 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/224
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Chemical compounds derived by in silico molecular modelling, having a well defined structure suitable for the blocking of the phosphorylation event, through the specific interaction of the chemical with the Casein Kinase 2 enzyme substrate phosphorylation domain or it's neighbourhood. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines or agents for the treatment of diseases or conditions related with neoplasic processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.