Triazole compounds that modulate Hsp90 activity

US8748424B2 · kind B2 · utility

Assignee

• Synta Pharmaceuticals Corp. · US

Inventors

• Dinesh U. Chimmanamada · Arlington, US
• Joseph A. Burlison · North Reading, US
• Weiwen Ying · Ayer, US
• Lijun Sun · Harvard, US
• Stefan M. Schweizer · Arlington, US
• Shijie Zhang · Nashua, US
• Zachary Demko · Los Altos, US
• David James · Cambridge, US
• Teresa Kowalczyk-Przewloka · Tewksbury, US

Key dates

• Filing date: Oct 26, 2012
• Grant date: Jun 10, 2014
• Expiry date: Oct 26, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to the use of a substituted triazole compound of the invention, or a composition comprising such a compound in the preparation of a medicament for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof.