Patent · US Active

Isolated A-type FHF N-terminal domain peptides and methods of use

US8748568B2 · kind B2 · utility

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1References

13Claims

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Assignee

RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK · US

Inventors

Mitchell Goldfarb · River Edge, US
Dover Katarzyna · Yonkers, US

Key dates

Filing date	May 6, 2010
Grant date	Jun 10, 2014
Priority date	—
Expiry date	May 13, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/861
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Isolated peptides are provided that are effective in inducing long-term inactivation of voltage-gated sodium channels (VGSCs) in mammalian cells. Such peptides are useful in reducing the action potentials of these excitable cells, for example, neurons, myocytes, and tonic muscle cells, in mammals in need thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.