Affinity ligands and methods for protein purification
US8748582B2 · kind B2 · utility
8Cited by
4References
15Claims
0Family size
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Key dates
| Filing date | Oct 15, 2010 |
| Grant date | Jun 10, 2014 |
| Priority date | — |
| Expiry date | Oct 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/22
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates generally to affinity ligands and chemical affinity ligand-matrix conjugates for use as chromatographic adsorbents and methods which utilize the adsorbents in the purification of proteins by affinity chromatography. The affinity ligand-matrix conjugates of the present invention comprise ligands of general formula (I): wherein m represents an integer from 0-2, n represents an integer from 0-6, p represents an integer from 0-4, R1 represents H or C1-3 alkyl, R2 is an optional substituent, and X is the position at which the ligand is immobilized, optionally via a linker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.