Methods and compositions for delivering interleukin-1 receptor antagonist
US8753690B2 · kind B2 · utility
29Cited by
30References
10Claims
0Family size
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Key dates
| Filing date | Aug 27, 2009 |
| Grant date | Jun 17, 2014 |
| Priority date | — |
| Expiry date | Oct 20, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions generating and using an interleukin-1 receptor antagonist (IL-1ra)-rich solution. Methods for generating and isolating interleukin-1 receptor antagonist include incubating adipose tissue and/or adipocytes with polyacrylamide beads to produce interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist is isolated from the polyacrylamide beads to obtain the solution rich in interleukin-1 receptor antagonist. Methods for treating a site of inflammation in a patient include administering to the site of inflammation the solution rich in interleukin-1 receptor antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.