Protease comprising one or more combinable mutations
US8753861B2 · kind B2 · utility
19Cited by
59References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 2009 |
| Grant date | Jun 17, 2014 |
| Priority date | — |
| Expiry date | Jun 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21062
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.