Biochip

US8753874B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Walter Gumbrecht · Herzogenaurach, DE
• Manfred Stanzel · Erlangen, DE

Key dates

• Filing date: Dec 15, 2003
• Grant date: Jun 17, 2014
• Expiry date: Jul 1, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5438
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A biochip includes a flat carrier and an array of spots containing catcher molecules which are arranged on the carrier. Each spot is associated with a microelectrode arrangement for impedance spectroscopic detection of binding events occurring between the catcher molecules and the target molecules applied via an analyte solution. In order to increase the sensitivity or the binding-specific measuring effects of the bio-chip, the electrode arrangement is at least partially embedded in a hydrophilic reaction layer containing catcher molecules and which is permeable to target molecules.