Method of differentiation of morula or inner cell mass cells and method of making lineage-defective embryonic stem cells
US8753884B2 · kind B2 · utility
1Cited by
4References
15Claims
0Family size
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Key dates
| Filing date | May 16, 2008 |
| Grant date | Jun 17, 2014 |
| Priority date | — |
| Expiry date | May 16, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An improved method of producing differentiated progenitor cells comprising obtaining inner cell mass cells from a blastocyst and inducing differentiation of the inner cell mass cells to produce differentiated progenitor cells. The differentiated progenitor cells may be transfected such that there is an addition, deletion or alteration of a desired gene. The differentiated progenitor cells are useful in cell therapy and as a I source of cells for the production of tissues and organs for transplantation. Also provided is a method of producing a lineage-defective human embryonic stem cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.