Patent · US Active

Modified C-3 betulinic acid derivatives as HIV maturation inhibitors

US8754068B2 · kind B2 · utility

7Cited by

4References

24Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Alicia Regueiro-Ren · Wallingford, US
Jacob Swidorski · Wallingford, US
Zheng Liu · Beacon Falls, US
Nicholas A. Meanwell · East Hampton, US
Sing-Yuen Sit · Meriden, US
Jie Chen · Houston, US
Ny Sin · East Hampton, US

Key dates

Filing date	Jun 2, 2011
Grant date	Jun 17, 2014
Priority date	—
Expiry date	Apr 13, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P37/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 betulinic acid and other structurally related natural products derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.