Macrocyclic inhibitors of hepatitis C virus

US8754105B2 · kind B2 · utility

Assignees

• MEDIVIR AB · SE
• Janssen R & D Ireland · IE

Inventors

• Kenneth Alan Simmen · Tervuren, BE
• Herman Augustinus De Kock · Arendonk, BE
• Pierre Jean-Marie Bernard Rabiosson · Bastogne, BE
• Abdellah Tahri · Anderlecht, BE
• Karl Magnus Nilsson · Vimmerby, SE
• Bengt Bertil Samuelsson · Skärholmen, SE
• Asa Annica Kristina Rosenquist · Huddinge, SE
• Dmitry Antonov · Huddinge, SE

Key dates

• Filing date: May 17, 2011
• Grant date: Jun 17, 2014
• Expiry date: May 17, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Inhibitors of HCV replication of formula (I)the N-oxides, salts, and stereochemically isomeric forms thereof, wherein each dashed line (represented by ) represents an optional double bond;