Flourescent dot counting in digital pathology images
US8755580B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2012 |
| Grant date | Jun 17, 2014 |
| Priority date | — |
| Expiry date | Oct 23, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V20/698
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Fluorescence in situ hybridization (FISH) enables the detection of specific DNA sequences in cell chromosomes by the use of selective staining. Due to the high sensitivity, FISH allows the use of multiple colors to detect multiple targets simultaneously. The target signals are represented as colored dots, and enumeration of these signals is called dot counting. Using a two-stage segmentation framework guarantees locating all potential dots including overlapped dots.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.