Patent · US Active

Stable lyophilized pharmaceutical preparations of monoclonal or polyclonal antibodies

US8758747B2 · kind B2 · utility

44Cited by

13References

3Claims

0Family size

Assignee

Roche Diagnostics GMBH · DE

Inventors

Georg KALLMEYER · Mannheim, DE
Gerhard Winter · Dossenheim, DE
Christian Klessen · Lauterecken, DE
Heinrich Woog · Hemsbach, DE

Key dates

Filing date	Jul 28, 2008
Grant date	Jun 24, 2014
Priority date	—
Expiry date	May 23, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention concerns lyophilized pharmaceutical preparations of monoclonal or polyclonal antibodies which contain a sugar or an amino sugar, an amino acid and a surfactant as stabilizers. In addition the invention concerns a process for the production of this stable lyophilizate as well as the use of a sugar or amino sugar, an amino acid and a surfactant as stabilizers for therapeutic or diagnostic agents containing antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.