Compositions and methods for treatment
US8758776B2 · kind B2 · utility
1Cited by
63References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 21, 2011 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Jan 21, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.