Anti-alpha2 integrin antibodies and their uses
US8759009B2 · kind B2 · utility
6Cited by
15References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2010 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Aug 17, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/7055
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.